Serveur d'exploration sur la grippe en Espagne

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[Burden of influenza virus type B and mismatch with the flu vaccine in Spain].

Identifieur interne : 000170 ( Main/Exploration ); précédent : 000169; suivant : 000171

[Burden of influenza virus type B and mismatch with the flu vaccine in Spain].

Auteurs : Jose Ma Eiros-Bouza [Espagne] ; Alberto Pérez-Rubio

Source :

RBID : pubmed:25690144

Descripteurs français

English descriptors

Abstract

INTRODUCTION

Since the 80s two lineages of type B viruses are co - circulating in the world. Antigenic differences between them are important and it leads to lack of cross-reactivity. The impact on the burden of disease due to influenza B virus, poor foresight in estimating which of the two lineages of B viruses circulate in the season, and the consequent lack of immunity in case of including the wrong strain make that the availability of the quadrivalent vaccine is very useful. The aim of this paper is to analyze the past influenza seasons in Spain to assess the burden of disease, divergence between the vaccine strain and the circulating B and viral characteristics associated with type B in each seasonal epidemic.

MATERIAL AND METHODS

Review of all reports issued by the Influenza Surveillance System in Spain since the 2003-2004 season to 2012-2013.

RESULTS

Over the past influenza seasons, although type A was present mostly, circulation of influenza B virus in each season was observed, even being co - dominant in some of them. In a high number of seasons the divergence between the vaccine strain and the circulating strain lineage has been observed

CONCLUSIONS

The protective effect of influenza vaccine has varied depending on the type / subtype of influenza virus studied. The vaccine effectiveness against influenza infection by influenza B virus has varied greatly depending on the season analyzed.


PubMed: 25690144


Affiliations:


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Le document en format XML

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<title xml:lang="en">[Burden of influenza virus type B and mismatch with the flu vaccine in Spain].</title>
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<name sortKey="Eiros Bouza, Jose Ma" sort="Eiros Bouza, Jose Ma" uniqKey="Eiros Bouza J" first="Jose Ma" last="Eiros-Bouza">Jose Ma Eiros-Bouza</name>
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<nlm:affiliation>Alberto Pérez Rubio. Dirección Médica. Hospital Clínico Universitario de Valladolid. Calle Ramón y Cajal 3, 47001. Valladolid, Spain. albertoprz@gmail.com.</nlm:affiliation>
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<term>Influenza B virus (MeSH)</term>
<term>Influenza Vaccines (immunology)</term>
<term>Influenza, Human (epidemiology)</term>
<term>Influenza, Human (immunology)</term>
<term>Influenza, Human (prevention & control)</term>
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<term>Résultat thérapeutique</term>
<term>Saisons</term>
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<b>INTRODUCTION</b>
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<p>Since the 80s two lineages of type B viruses are co - circulating in the world. Antigenic differences between them are important and it leads to lack of cross-reactivity. The impact on the burden of disease due to influenza B virus, poor foresight in estimating which of the two lineages of B viruses circulate in the season, and the consequent lack of immunity in case of including the wrong strain make that the availability of the quadrivalent vaccine is very useful. The aim of this paper is to analyze the past influenza seasons in Spain to assess the burden of disease, divergence between the vaccine strain and the circulating B and viral characteristics associated with type B in each seasonal epidemic.</p>
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<b>MATERIAL AND METHODS</b>
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<p>Review of all reports issued by the Influenza Surveillance System in Spain since the 2003-2004 season to 2012-2013.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>RESULTS</b>
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<p>Over the past influenza seasons, although type A was present mostly, circulation of influenza B virus in each season was observed, even being co - dominant in some of them. In a high number of seasons the divergence between the vaccine strain and the circulating strain lineage has been observed</p>
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<p>
<b>CONCLUSIONS</b>
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<p>The protective effect of influenza vaccine has varied depending on the type / subtype of influenza virus studied. The vaccine effectiveness against influenza infection by influenza B virus has varied greatly depending on the season analyzed.</p>
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